Promoter hypermethylation of the 14-3-3 sigma, SYK and CAGE-1 genes is related to the various phenotypes of urinary bladder carcinomas and associated with progression of transitional cell carcinomas.

Abstract excerpt

To explore the significance of epigenetic mechanisms in urinary bladder carcinogenesis mediated by methylation of cytosine in CpG dinucleotides at 5' promoter regions, we analysed the methylation status of a broad panel of different genes in transitional cell carcinomas (TCC) and nonurothelial ca...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to 14-3-3 Proteins
• Share to Carcinoma, Transitional Cell
• Share to Core Binding Factor Alpha 3 Subunit