Article
Induced cerebral hypothermia reduces post-hypoxic loss of phenotypic striatal neurons in preterm fetal sheep.
Experimental neurology - 1 Jan 2007
George S, Scotter J, Dean J M, Bennet L, Waldvogel H J, Guan J, Faull R L M, Gunn A J
Abstract excerpt
Perinatal hypoxic-ischemic injury of the basal ganglia is a significant cause of disability in premature infants. Prolonged, moderate cerebral hypothermia has been shown to be neuroprotective after experimental hypoxia-ischemia; however, it has not been tested in the preterm brain. We therefore examined the effects of severe hypoxia and the potential neuroprotective effects of delayed hypothermia on phenotypic...
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