Article
[The analysis of genomic mutations and structural chromosome aberrations in irradiated human lymphocytes].
Radiatsionnaia biologiia, radioecologiia - 1 Jan 2000
Riabchenko N I, Fesenko E V, Antoshchina M M, Nasonova V A, Kondrashova T V
Abstract excerpt
The lymphocytes of healthy donors were exposed to 60Co gamma-rays in doses ranging 0.5 to 6.0 Gy, and were incubated with PHA and 5-bromodeoxyuridine at 37 degrees C for 72 h. In the course of five consecutive in vitro divisions of cultured lymphocytes, the frequency of polyploid metaphases were determined, and chromosome structural aberrations in polyploid and diploid metaphases were analyzed. Dose dependence of...
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