Article
Correlation among pathology, genotype, and patient outcomes in glioblastoma.
Journal of neuropathology and experimental neurology - 1 Sept 2006
Homma Taku, Fukushima Takao, Vaccarella Salvatore, Yonekawa Yasuhiro, Di Patre Pier Luigi, Franceschi Silvia, Ohgaki Hiroko
Abstract excerpt
Glioblastomas are histologically and genetically heterogeneous. We have investigated to what extent histologic features reflect the genetic profile and whether they are predictive of clinical outcome. Key histologic characteristics, including major cell types (small cell, nonsmall cell), other components such as oligodendroglial components, gemistocytes, multinucleated giant cells, as well as necrosis and...
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