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Article

Glioblastoma with oligodendroglioma component (GBM-O): molecular genetic and clinical characteristics.

Brain pathology (Zurich, Switzerland) - 1 Jul 2013

Appin Christina L, Gao Jingjing, Chisolm Candace, Torian Mike, Alexis Dianne, Vincentelli Cristina, Schniederjan Matthew J, Hadjipanayis Costas, Olson Jeffrey J, Hunter Stephen, Hao Chunhai, Brat Daniel J

Abstract excerpt

Glioblastoma (GBM) is an aggressive primary brain tumor with an average survival of approximately 1 year. A recently recognized subtype, glioblastoma with oligodendroglioma component (GBM-O), was designated by the World Health Organization (WHO) in 2007. We investigated GBM-Os for their clinical and molecular characteristics as compared to other forms of GBM. Tissue samples were used to determine EGFR, PTEN, and...

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Source

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Identifiers

PMID: 23289977
DOI: 10.1111/bpa.12018
PMCID: PMC4868066

Genes

IDH1
PTEN
EGFR
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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