Article
Difference between evolutionarily effective and germ line mutation rate due to stochastically varying haplogroup size.
Molecular biology and evolution - 1 Dec 2006
Zhivotovsky Lev A, Underhill Peter A, Feldman Marcus W
Abstract excerpt
Within a Y-chromosome haplogroup defined by unique event mutations, variation in microsatellites can accumulate due to their rapid mutation. Estimates based on pedigrees for the Y-chromosome microsatellite mutation rate are 3 or more times greater than the same estimates from evolutionary considerations. We show by simulation that the haplogroups that survive the stochastic processes of drift and extinction...
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