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Article

Solution NMR and computer simulation studies of active site loop motion in triosephosphate isomerase.

Biochemistry - 12 Sept 2006

Massi Francesca, Wang Chunyu, Palmer Arthur G

Abstract excerpt

Solution NMR spin relaxation experiments and classical MD simulations are used to study the dynamics of triosephosphate isomerase (TIM) in complex with glycerol 3-phosphate (G3P). Three regions in TIM exhibit conformational transitions on the micros-ms time scale as detected by chemical exchange...

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PMID: 16953564
DOI: 10.1021/bi060764c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16953564-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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