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Article

DnaJA4 is a SREBP-regulated chaperone involved in the cholesterol biosynthesis pathway.

Biochimica et biophysica acta - 1 Sept 2006

Robichon Céline, Varret Mathilde, Le Liepvre Xavier, Lasnier Françoise, Hajduch Eric, Ferré Pascal, Dugail Isabelle

Abstract excerpt

Using subtractive hybridization technique in 3T3-L1 adipocytes overexpressing constitutively active SREBP2, we have identified a DnaJ/Hsp40 chaperone, DnaJA4, as a new SREBP-responsive gene. SREBP2 regulation was demonstrated by changes in DnaJA4 mRNA under conditions of altered sterol status tha...

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Identifiers

PMID: 16950652
DOI: 10.1016/j.bbalip.2006.07.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16950652-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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