Article
Analysis of respiratory syncytial virus genetic variability with amplified cDNAs.
Journal of clinical microbiology - 1 May 1993
Sullender W M, Sun L, Anderson L J
Abstract excerpt
Antigenic and genetic heterogeneities exist within the two major antigenic groups of respiratory syncytial (RS) virus. We developed a polymerase chain reaction (PCR)-based assay that not only differentiates the two RS virus groups but allows distinctions within groups on the basis of changes in the nucleotide sequences, as revealed by restriction fragment analysis. In this assay, viral RNA served as a template...
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