Article
Polymorphisms of IL-10 gene in patients infected with HCV under antiviral treatment in southern Brazil.
Cytokine - 1 Jun 2015
da Silva Naylê Maria Oliveira, Germano Fabiana Nunes, Vidales-Braz Beatris Maria, Carmo Zanella Ricardo do, dos Santos Deise Machado, Lobato Rubens, de Martinez Ana Maria Barral
Abstract excerpt
Interleukin-10 (IL-10) is a cytokine that plays an important role in the regulation of the immune system. Gene polymorphisms of IL-10 have been associated with the different expression levels of this cytokine. In hepatitis C virus infection, IL-10 appears to interfere with the progression of disease, viral persistence and the response to therapy. This study investigated genetic variability in the IL-10 gene...
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