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Article

Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodes.

Proceedings of the National Academy of Sciences of the United States of America - 5 Sept 2006

Coles Mark C, Veiga-Fernandes Henrique, Foster Katie E, Norton Trisha, Pagakis Stamatis N, Seddon Ben, Kioussis Dimitris

Abstract excerpt

Lymph node (LN) development depends on prenatal interactions occurring between LN inducer and LN organizer cells. We have distinguished defects in LN formation due to failure in embryonic development (aly/aly) from defects in postnatal maturation (Il2rgamma(-/-)Rag2(-/-)). Both mutant strains form normal primordial LNs with differing fate. In aly/aly mice, the LN primordium dissipates irreversibly late in...

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Identifiers

PMID: 16938836
DOI: 10.1073/pnas.0604183103
PMCID: PMC1569185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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