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Article

HepG2 cells support viral replication and gene expression of hepatitis C virus genotype 4 in vitro.

World journal of gastroenterology - 14 Aug 2006

el-Awady Mostafa K, Tabll Ashraf A, el-Abd Yasmine S, Bahgat Mahmoud M, Shoeb Hussein A, Youssef Samar S, Bader el-Din Noha G, Redwan el-Rashdy M, el-Demellawy Maha, Omran Moataza H, el-Garf Wael T, Goueli Said A

Abstract excerpt

AIM: To establish a cell culture system with long-term replication of hepatitis C virus (HCV) genome and expression of viral antigens in vitro. METHODS: HepG2 cell line was tested for its susceptibility to HCV by incubation with a serum from a patient with chronic hepatitis C. Cells and supernatant were harvested at various time points during the culture. Culture supernatant was tested for its ability to infect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16937465
DOI: 10.3748/wjg.v12.i30.4836
PMCID: PMC4087617

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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