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Article

DNA mutation analysis in heterotaxy.

Methods in molecular medicine - 1 Jan 2006

Ware Stephanie M

Abstract excerpt

Heterotaxy refers to the abnormal arrangement of internal organs in relation to each other. It is characterized by complex cardiac malformations that are thought to result from abnormal left-right patterning in early embryonic development. Mutations in four genes have been identified in human heterotaxy. ZIC3, a zinc finger transcription factor, causes X-linked heterotaxy. EGF-CFC, ACVR2B, and LEFTYA are all...

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Source

Identifiers

PMID: 16930017
DOI: 10.1385/1-59745-088-X:247

Genes

ZIC3
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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DNA mutation analysis in heterotaxy.PMID 16930017Read ↗

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