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Article

Mutations in ZIC3 and ACVR2B are a common cause of heterotaxy and associated cardiovascular anomalies.

Cardiology in the young - 1 Apr 2012

Ma Lijiang, Selamet Tierney Elif Seda, Lee Teresa, Lanzano Patricia, Chung Wendy K

Abstract excerpt

BACKGROUND: Heterotaxy syndrome is caused by left-right asymmetry disturbances and is associated with abnormal lateralisation of the abdominal and thoracic organs. The heart is frequently involved and the severity of the abnormality usually determines the outcome. METHODS: We performed a direct sequence analysis of the coding sequence of genes including Zinc Finger Protein of the Cerebellum 3, Left-Right...

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Identifiers

PMID: 21864452
DOI: 10.1017/S1047951111001181
PMCID: PMC3678527

Genes

ZIC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Mutations in ZIC3 and ACVR2B are a common cause of heterotaxy and associated cardiovascular anomalies.PMID 21864452Read ↗

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