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Generation and Analysis of Infectious Virus-Like Particles of Uukuniemi Virus ( <i>Bunyaviridae</i> ): a Useful System for Studying Bunyaviral Packaging and Budding

15 Oct 2006

Abstract excerpt

In the present report we describe an infectious virus-like particle (VLP) system for the Uukuniemi (UUK) virus, a member of the Bunyaviridae family. It utilizes our recently developed reverse genetic system based on the RNA polymerase I minigenome system for UUK virus used to study replication, encapsidation, and transcription by monitoring reporter gene expression. Here, we have added the glycoprotein precursor...

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PMID: 16928751
DOI: 10.1128/jvi.01362-06

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