Article
Expression and function of a family of transmembrane kinases from the protozoan parasite Entamoeba histolytica.
Infection and immunity - 1 Sept 2006
Mehra Alka, Fredrick Jesse, Petri William A, Bhattacharya Sudha, Bhattacharya Alok
Abstract excerpt
The signaling proteome of Entamoeba histolytica is made of transmembrane kinases (TMKs) that are rarely found in unicellular eukaryotes. There are 90 TMK genes reported for E. histolytica, and these have been grouped into nine distinct families based on motifs present on both extracellular and kinase domains. Of these, the B1 family was chosen for further analysis. Genomic sequencing revealed the presence of 28...
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