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Identification of anEntamoeba histolyticaSerine-, Threonine-, and Isoleucine-Rich Protein with Roles in Adhesion and Cytotoxicity

8 Sept 2007

Abstract excerpt

Entamoeba histolytica is a leading cause of parasitic death globally. However, the molecular framework regulating pathogenesis is poorly understood. We have previously used expression profiling to identify Entamoeba genes whose expressions were strictly associated with virulent strains (R. C. MacFarlane and U. Singh, Infect. Immun. 74:340-351, 2006). One gene, which we have named EhSTIRP (Entamoeba histolytica...

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PMID: 17827347
DOI: 10.1128/ec.00174-07

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