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Article

Unchanged scrapie pathology in brain tissue of tyrosine kinase Fyn-deficient mice.

Neuro-degenerative diseases - 1 Jan 2004

Schwarz Anja, Burwinkel Michael, Riemer Constanze, Schultz Julia, Baier Michael

Abstract excerpt

Fyn is a 59-kDa member of the Src family of tyrosine kinases synthesized on cytosolic polysomes and then targeted to the plasma membrane where it clusters in caveolae-like membrane microdomains. The cellular isoform of the prion protein (PrP) has also been identified to be a caveolar constituent and to participate in signal transduction events concerning cell survival and differentiation via recruitment of Fyn....

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Identifiers

PMID: 16908977
DOI: 10.1159/000085065

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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