Article
The mitochondrial citrate transport protein: evidence for a steric interaction between glutamine 182 and leucine 120 and its relationship to the substrate translocation pathway and identification of other mechanistically essential residues.
Biochimica et biophysica acta - 1 Jan 2000
Ma Chunlong, Remani Sreevidya, Kotaria Rusudan, Mayor June A, Walters D Eric, Kaplan Ronald S
Abstract excerpt
Previous examination of the accessibility of a panel of single-Cys mutants in transmembrane domain III (TMDIII) of the yeast mitochondrial citrate transport protein to the hydrophilic, cysteine-specific methanethiosulfonate reagent MTSES enabled identification of the water-accessible surface of this TMD. Further studies on the effect of citrate on MTS reagent accessibility, indicated eight sites within TMD III at...
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