Therapeutic administration of recombinant human granulocyte colony‐stimulating factor accelerates hemopoietic regeneration and enhances survival in a murine model of radiation‐induced myelosuppression

Abstract excerpt

The primary cause of death after radiation exposure is infection resulting from myelosuppression. Because granulocytes play a critical role in host defense against infection and because granulocyte proliferation and differentiation are enhanced by granulocyte colony-stimulating factor (G-CSF), this agent was evaluated for the ability to accelerate hemopoietic regeneration and to enhance survival in irradiated...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Effects of Radiation Exposure
• Share to Neutropenia and Cancer Infections