Article
Genetic analysis of the stress-responsive adrenocortical axis.
Physiological genomics - 27 Nov 2006
Solberg Leah C, Baum Amber E, Ahmadiyeh Nasim, Shimomura Kazuhiro, Li Renhua, Turek Fred W, Takahashi Joseph S, Churchill Gary A, Redei Eva E
Abstract excerpt
The underlying genetic components contributing to individual variability in functions of the stress-responsive hypothalamic-pituitary-adrenal (HPA) axis are poorly understood. To determine genetic loci mediating three aspects of the adrenocortical function, we conducted a quantitative trait locus (QTL) analysis in the segregating F2 generation of a Wistar Kyoto (WKY) x Fischer 344 (F344) cross, two inbred rat...
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