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Article

Creation of novel Protein Transduction Domain (PTD) mutants by a phage display-based high-throughput screening system.

Biological & pharmaceutical bulletin - 1 Aug 2006

Mukai Yohei, Sugita Toshiki, Yamato Tomoko, Yamanada Natsue, Shibata Hiroko, Imai Sunao, Abe Yasuhiro, Nagano Kazuya, Nomura Tetsuya, Tsutsumi Yasuo, Kamada Haruhiko, Nakagawa Shinsaku, Tsunoda Shin-ichi

Abstract excerpt

Significant research effort is currently focused on Protein Transduction Domains (PTDs) as potential intracellular drug delivery carriers. However, the application of this technology is limited because the transduction efficiencies are often insufficient for therapeutic purposes, even using HIV-1 Tat peptide. Here we describe a high-throughput screening method based on a phage display system for isolating novel...

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PMID: 16880606
DOI: 10.1248/bpb.29.1570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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