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Article

Evidence for association between the HLA-DQA locus and abdominal aortic aneurysms in the Belgian population: a case control study.

BMC medical genetics - 31 Jul 2006

Ogata Toru, Gregoire Lucie, Goddard Katrina A B, Skunca Magdalena, Tromp Gerard, Lancaster Wayne D, Parrado Antonio R, Lu Qing, Shibamura Hidenori, Sakalihasan Natzi, Limet Raymond, MacKean Gerald L, Arthur Claudette, Sueda Taijiro, Kuivaniemi Helena

Abstract excerpt

BACKGROUND: Chronic inflammation and autoimmunity likely contribute to the pathogenesis of abdominal aortic aneurysms (AAAs). The aim of this study was to investigate the role of autoimmunity in the etiology of AAAs using a genetic association study approach with HLA polymorphisms. METHODS: HLA-DQA1, -DQB1, -DRB1 and -DRB3-5 alleles were determined in 387 AAA cases (180 Belgian and 207 Canadian) and 426 controls...

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Share to Aortic Aneurysm, Abdominal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16879749
DOI: 10.1186/1471-2350-7-67
PMCID: PMC1559600

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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