Article
Production of novel fusarielins by ectopic activation of the polyketide synthase 9 cluster in Fusarium graminearum.
Environmental microbiology - 1 May 2012
Sørensen Jens Laurids, Hansen Frederik Teilfeldt, Sondergaard Teis Esben, Staerk Dan, Lee T Verne, Wimmer Reinhard, Klitgaard Louise Graabaek, Purup Stig, Giese Henriette, Frandsen Rasmus John Normand
Abstract excerpt
Like many other filamentous fungi, Fusarium graminearum has the genetic potential to produce a vast array of unknown secondary metabolites. A promising approach to determine the nature of these is to activate silent secondary metabolite gene clusters through constitutive expression of cluster specific transcription factors. We have developed a system in which an expression cassette containing the transcription...
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