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Article

Microfluidic isolation of leukocytes from whole blood for phenotype and gene expression analysis.

Analytical chemistry - 1 Aug 2006

Sethu Palaniappan, Moldawer Lyle L, Mindrinos Michael N, Scumpia Philip O, Tannahill Cynthia L, Wilhelmy Julie, Efron Philip A, Brownstein Bernard H, Tompkins Ronald G, Toner Mehmet

Abstract excerpt

Technologies that enable the isolation of cell subtypes from small samples of complex populations will greatly facilitate the implementation of proteomics and genomics to human diseases. Transcriptome analysis of blood requires the depletion of contaminating erythrocytes. We report an automated microfluidic device to rapidly deplete erythrocytes from whole blood via deionized water lysis and to collect enriched...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16878882
DOI: 10.1021/ac060140c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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