Article
Association study of sporadic Parkinson's disease genetic risk factors in patients from Russia by APEX technology.
Neuroscience letters - 25 Sept 2006
Shadrina Maria, Nikopensius Tiit, Slominsky Petr, Illarioshkin Sergei, Bagyeva Gulbahar, Markova Elene, Ivanova-Smolenskaia Irina, Kurg Ants, Limborska Svetlana, Metspalu Andres
Abstract excerpt
Most patients with Parkinson's disease (PD) have sporadic form of the disease with a multifactorial etiology due to interactions between environmental conditions and the genetic constitution of the individuals. We have analyzed by APEX technology 50 single nucleotide polymorphisms (SNPs) in 19 genes related to cholecystokinin, serotonin, dopamine and opioid neurotransmission. Significant differences in the allele...
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