Correlation of SV2C rs1423099 single nucleotide polymorphism with sporadic Parkinson's disease in Han population in Southern China.

doi:10.1016/j.neulet.2023.137426

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Correlation of SV2C rs1423099 single nucleotide polymorphism with sporadic Parkinson's disease in Han population in Southern China.

Neuroscience letters - 14 Sept 2023

Tan Zixin, Lin Yuwan, Zhou Miaomiao, Guo Wenyuan, Qiu Jiewen, Ding Liuyan, Wu Zhuohua, Xu Pingyi, Chen Xiang

Abstract excerpt

BACKGROUND: The synaptic vesicle glycoprotein 2 (SV2) has been implicated in synaptic function throughout the brain. Accumulating evidence investigated that SV2C contributed to dopamine release and the disrupted expression of SV2C was considered to be a unique feature of PD that may facilitate dopaminergic neuron dysfunction. OBJECTIVE: This study aimed to examine the relationship between the SV2C rs1423099...

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PMID: 37544580
DOI: 10.1016/j.neulet.2023.137426

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