Article
[Study of genes involved in chronic myeloid leukemia with t (3; 21) (q26; q22) in blastic crisis].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 May 2006
Liu Xu-ping, Zhang Mei-rong, Dai Yun, Zhang Li, Li Rui, Hao Yu-shu, Xiao Zhi-jian
Abstract excerpt
OBJECTIVE: To explore genes involved in chronic myeloid leukemia (CML) with t (3; 21) (q26; q22) chromosome translocation in blastic crisis. METHODS: A case of CML patient with t (3; 21) (q26; q22) in blastic crisis was reported. AML1 and bcr/abl genes were detected by FISH in interphase and metaphase cells. Genes involved in t (3; 21) (q26; q22) were analysed by RT-PCR and sequencing. RESULTS: AML1 gene...
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