Article
The dynamics of autophagy visualized in live cells: from autophagosome formation to fusion with endo/lysosomes.
Autophagy - 1 Apr 2005
Bampton Edward T W, Goemans Christoph G, Niranjan Dhevahi, Mizushima Noboru, Tolkovsky Aviva M
Abstract excerpt
Autophagy has been implicated in a range of disorders and hence is of major interest. However, imaging autophagy in real time has been hampered by lack of suitable markers. We have compared the potential of monodansylcadaverine, widely used as an autophagosomal marker, and the Atg8 homologue LC3, to follow autophagy by fluorescence microscopy whilst labelling late endosomes and lysosomes simultaneously using...
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