Article
Evaluation of the epidermal growth factor receptor gene mutation and copy number in non-small cell lung cancer with gefitinib therapy.
Oncology reports - 1 Sept 2006
Endo Katsuhiko, Sasaki Hidefumi, Yano Motoki, Kobayashi Yoshihiro, Yukiue Haruhiro, Haneda Hiroshi, Suzuki Eriko, Kawano Osamu, Fujii Yoshitaka
Abstract excerpt
Several studies have suggested that epidermal growth factor receptor (EGFR) gene mutation, EGFR gene amplification, and some other biomarkers may be predictors of gefitinib sensitivity. We analyzed EGFR mutation and EGFR copy number in 22 gefitinib-treated non-small cell lung cancer (NSCLC) cases...
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