Article
Men transmit MS more often to their children vs women: the Carter effect.
Neurology - 25 Jul 2006
Kantarci O H, Barcellos L F, Atkinson E J, Ramsay P P, Lincoln R, Achenbach S J, De Andrade M, Hauser S L, Weinshenker B G
Abstract excerpt
OBJECTIVE: Multiple sclerosis (MS) is approximately twice as common among women as men. If men have greater physiologic resistance to MS, they might theoretically require stronger genetic predisposition than women to overcome this resistance. In this circumstance, men would be expected to transmit the disease more often to their children, a phenomenon known as the Carter effect. The authors evaluated whether the...
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