Article
[Relationship of collagen type I alpha 1 and alpha 2 gene polymorphisms with bone mineral density].
Nan fang yi ke da xue xue bao = Journal of Southern Medical University - 1 Jul 2006
Li Dong-feng, Wu Wen, Cai Xue-zhen, Yang Yan-hong, Lin Kai, Huang Xiao-sui, Dong Ting, Zhi Xi-mei
Abstract excerpt
OBJECTIVE: To investigate collagen type I alpha 1 (COL1A1) and alpha 2 (COL1A2) gene polymorphisms in Chinese and their relationship with bone mineral density. METHODS: Totalling 628 residents of Han nationality in Guangzhou aged 53.4-15.9 (range 20-79) years were surveyed for COL1A1 and COL1A2 gene genotypes by polymerase chain reaction-restriction fragment length polymorphism. Bone mineral density of the lumbar...
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