Article
Contribution of CYP2C9 to variability in vitamin K antagonist metabolism.
Expert opinion on drug metabolism & toxicology - 1 Feb 2006
Daly Ann K, King Barry P
Abstract excerpt
CYP2C9 is the third most important cytochrome P450 (CYP) in terms of number of drugs metabolised. A considerable amount of information on this isoform is now available with respect to its structural biology, the mechanisms by which it can be induced and the existence of a range of variant alleles, which are often functionally significant. CYP2C9 makes a very important contribution to metabolism of vitamin K...
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