X-linked immunodeficiencies: clues to genes involved in T- and B-cell differentiation.

doi:10.1016/0167-5699(91)90019-p

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Article

X-linked immunodeficiencies: clues to genes involved in T- and B-cell differentiation.

Immunology today - 1 Dec 1991

de Saint Basile G, Fischer A

Abstract excerpt

There are five major human X-linked immunodeficiencies, each with a characteristic impairment of T-and/or B-cell differentiation. The molecular bases of these diseases remain unknown but, as Geneviève de Saint Basile and Alain Fischer report, major steps towards that goal have been taken: the loc...

Topics

Animals
B-Lymphocytes
Cell Differentiation
Chromosome Mapping
Disease Models, Animal
Dog Diseases
Dogs
Dosage Compensation, Genetic
Female
Gene Expression Regulation
Genetic Linkage
Genetic Markers
Heterozygote
Humans
Immunologic Deficiency Syndromes
Male
Mice
Mice, Mutant Strains

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