Article
X-linked immunodeficiencies: clues to genes involved in T- and B-cell differentiation.
Immunology today - 1 Dec 1991
de Saint Basile G, Fischer A
Abstract excerpt
There are five major human X-linked immunodeficiencies, each with a characteristic impairment of T-and/or B-cell differentiation. The molecular bases of these diseases remain unknown but, as Geneviève de Saint Basile and Alain Fischer report, major steps towards that goal have been taken: the location of the defective genes has been precisely defined and the cell lineages and stages of differentiation in which...
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