Breakthroughs in the understanding and therapy of primary immunodeficiency.

Abstract excerpt

In the 40 years since Ogden Bruton discovered agammaglobulinemia, more than 50 additional immunodeficiency syndromes have been described. Until recently, there was little insight into the fundamental problems underlying a majority of these conditions. Recently, however, the molecular bases of thr...

Topics

• B-Lymphocytes
• Bone Marrow Transplantation
• Chromosome Mapping
• Humans
• Immunoglobulins, Intravenous
• Immunologic Deficiency Syndromes
• Molecular Biology
• Mutation
• T-Lymphocytes