Article
Duplication, gene conversion, and genetic diversity in the species-specific acyl-CoA synthetase gene family of Plasmodium falciparum.
Molecular and biochemical parasitology - 1 Nov 2006
Bethke Lara L, Zilversmit Martine, Nielsen Kaare, Daily Johanna, Volkman Sarah K, Ndiaye Daouda, Lozovsky Elena R, Hartl Daniel L, Wirth Dyann F
Abstract excerpt
While genes encoding antigens and other highly polymorphic proteins are commonly found in subtelomeres, it is unusual to find a small family of housekeeping genes in these regions. We found that in the species Plasmodium falciparum only, a non-subtelomeric acyl-CoA synthetase (ACS) gene has expanded into a family of duplicated genes mainly located in the subtelomeres of the genome. We identified the putative...
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