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Article

Pediatric patients with essential thrombocythemia are mostly polyclonal and V617FJAK2 negative

18 Jul 2006

Abstract excerpt

Essential thrombocythemia (ET) is rare in children, and little or no information is available about clonality or JAK2 mutations. However, the analyses in this work prove useful for the diagnosis of adult myeloproliferative disorders (MPDs). We evaluated the clonality status and V617FJAK2 mutation in 20 children affected by ET and compared them with 47 consecutive adult ET cases. Clonality was evaluated on the DNA...

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PMID: 16849644
DOI: 10.1182/blood-2006-04-014746

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