Article
Childhood and adolescent essential thrombocythemia and prefibrotic primary myelofibrosis: insights into diagnosis, outcomes, and treatment from a large Chinese cohort.
Leukemia - 1 Jan 2025
Fu Rongfeng, Dong Huan, Gu Wenjing, Meng Ke, Sun Ting, Liu Xiaofan, Qu Xinmiao, Chen Jia, Xue Feng, Liu Wei, Chen Yunfei, Ju Mankai, Dai Xinyue, Chi Ying, Wang Wentian, Pei Xiaolei, Zhu Xiaofan, Yang Renchi, Li Huiyuan, Zhang Lei
Abstract excerpt
The paucity of essential thrombocythemia (ET) and prefibrotic primary myelofibrosis (pre-PMF) in individuals younger than 18 years highlights several unresolved issues in diagnosis, clinical outcomes, and treatment strategies. To address these knowledge gaps, we analyzed a large bidirectional cohort consisting of childhood and adolescent ET (CAA-ET, n = 156) and pre-PMF (CAA-preMF, n = 13), as well as adult ET...
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