Article
Estimating allele frequencies of hypervariable DNA systems.
Forensic science international - 1 Oct 1991
Pascali V L, d'Aloja E, Dobosz M, Pescarmona M
Abstract excerpt
Several polymorphisms of human DNA have been shown to be hypervariable due to the recurrence of a variable number of tandem repeats (VNTRs) in the lengths of allelic restriction fragments. The recurrence of allelic variants in this novel class of polymorphisms seems to comply well with a model of continuous random variables. Based on this assumption, we have compiled some simple algorithms for classification of...
Topics
- Algorithms
- Alleles
- DNA
- Gene Frequency
- Humans
- Polymorphism, Restriction Fragment Length
- Repetitive Sequences, Nucleic Acid
- Restriction Mapping
- Software