Article
A species dependent response to the pro-epileptic drug pentylentetrazole in birds.
Brain research bulletin - 1 Sept 2017
Amin Faiq, Dar Asim H, Osama Khan, Khan Faezah, Mitha Rida, Tharwani Arsal, Haider Ghulam, Chand Prem, Arain Fazal M
Abstract excerpt
Epilepsy is common disorder that affects over 50 million people worldwide. Birds remain a promising yet largely under-explored model of epilepsy. This study reports the comparison of the response of two species of birds, Australian Parrots (APs) and Sparrows (SPs), to a pro-epileptic drug, Pentylenetetrazole (PTZ). PTZ injections caused myoclonic jerks (MCJs) and tonic clonic seizures (TCSs) in both species. The...
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