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Article

A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.

Nature genetics - 1 Aug 2006

Ozaki Kouichi, Sato Hiroshi, Iida Aritoshi, Mizuno Hiroya, Nakamura Takahiro, Miyamoto Yoshinari, Takahashi Atsushi, Tsunoda Tatsuhiko, Ikegawa Shiro, Kamatani Naoyuki, Hori Masatsugu, Nakamura Yusuke, Tanaka Toshihiro

Abstract excerpt

Inflammation is now considered critical in the pathogenesis of myocardial infarction. One of the mechanisms regulating the inflammatory process is the ubiquitin-proteasome system. We investigated whether variants of the 20S proteasome are associated with susceptibility to myocardial infarction an...

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Source

Identifiers

PMID: 16845397
DOI: 10.1038/ng1846

Genes

PSMA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16845397-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

A functional SNP in PSMA6 confers risk of myocardial infarction in the Japanese population.PMID 16845397Read ↗

Validation of the association between the gene encoding proteasome subunit alpha type 6 and myocardial infarction in a Japanese population.Semantic proximity Read ↗

The functional variant rs1048990 in PSMA6 is associated with susceptibility to myocardial infarction in a Chinese population.Semantic proximity Read ↗

The exon 1-8C/G SNP in the PSMA6 gene contributes only a small amount to the burden of myocardial infarction in 6946 cases and 2720 controls from a United Kingdom population.Semantic proximity Read ↗

The -8 UTR C/G polymorphism of PSMA6 gene is associated with susceptibility to myocardial infarction in type 2 diabetic patients.Semantic proximity Read ↗

Quantitative assessment of the influence of PSMA6 variant (rs1048990) on coronary artery disease risk.Semantic proximity Read ↗

Replication studies for the association of PSMA6 polymorphism with coronary artery disease in East Asian populations.Semantic proximity Read ↗

Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21.Semantic proximity Read ↗

Association between functional variant of inflammatory system gene (PSMA6) and end-stage kidney disease.Semantic proximity Read ↗

Identification of STXBP2 as a novel susceptibility locus for myocardial infarction in Japanese individuals by an exome-wide association study.Semantic proximity Read ↗

Genome-wide association study to identify SNPs conferring risk of myocardial infarction and their functional analyses.Semantic proximity Read ↗

Association of six genetic variants with myocardial infarction.Semantic proximity Read ↗

Sequence Variants of SIRT6 Gene Promoter in Myocardial Infarction.Semantic proximity Read ↗

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