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Article

Increased p21-activated kinase-1 expression is associated with invasive potential in uveal melanoma.

Melanoma research - 1 Aug 2006

Pavey Sandra, Zuidervaart Wieke, van Nieuwpoort Frans, Packer Leisl, Jager Martine, Gruis Nelleke, Hayward Nicholas

Abstract excerpt

Prognosis in patients with uveal melanoma is poor as approximately half of all tumors metastasize and currently there are no effective treatments for disseminated disease. Differences in invasiveness between uveal melanomas could therefore be of major significance regarding clinical outcome. To identify genes associated with invasive potential, we have used microarray expression profiling combined with phenotypic...

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Source

Identifiers

PMID: 16845324
DOI: 10.1097/01.cmr.0000222589.30117.f2

Genes

PAK1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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