Article
Regulation of cancer aggressive features in melanoma cells by microRNAs.
PloS one - 25 Apr 2011
Greenberg Eyal, Hershkovitz Liat, Itzhaki Orit, Hajdu Steven, Nemlich Yael, Ortenberg Rona, Gefen Nir, Edry Liat, Modai Shira, Keisari Yona, Besser Michal J, Schachter Jacob, Shomron Noam, Markel Gal
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNAs with regulatory roles, which are involved in a broad spectrum of physiological and pathological processes, including cancer. A common strategy for identification of miRNAs involved in cell transformation is to compare malignant cells to normal cells. Here we focus on identification of miRNAs that regulate the aggressive phenotype of melanoma cells. To avoid differences...
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