Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

siVirus: web-based antiviral siRNA design software for highly divergent viral sequences.

Nucleic acids research - 1 Jul 2006

Naito Yuki, Ui-Tei Kumiko, Nishikawa Toru, Takebe Yutaka, Saigo Kaoru

Abstract excerpt

siVirus (http://siVirus.RNAi.jp/) is a web-based online software system that provides efficient short interfering RNA (siRNA) design for antiviral RNA interference (RNAi). siVirus searches for functional, off-target minimized siRNAs targeting highly conserved regions of divergent viral sequences. These siRNAs are expected to resist viral mutational escape, since their highly conserved targets likely contain...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Antiviral Agents
Share to Conserved Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Internet

Share to RNA Interference

Share to RNA, Small Interfering

Share to RNA Viruses

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 16845046
DOI: 10.1093/nar/gkl214
PMCID: PMC1538817

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

siVirus: web-based antiviral siRNA design software for highly divergent viral sequences.PMID 16845046Read ↗

<i>In Silico</i> Design of siRNAs Targeting Existing and Future Respiratory Viruses with VirusSiSemantic proximity Read ↗

An in silico analysis of effective siRNAs against COVID‐19 by targeting the leader sequence of SARS‐CoV‐2Semantic proximity Read ↗

Biochemistry-informed design selects potent siRNAs against SARS-CoV-2Semantic proximity Read ↗

A small interfering RNA (siRNA) database for SARS-CoV-2Semantic proximity Read ↗

In Silico and In Vitro development of novel small interfering RNAs (siRNAs) to inhibit SARS-CoV-2Semantic proximity Read ↗

In Silico Design and Experimental Validation of siRNAs Targeting Conserved Regions of Multiple Hepatitis C Virus Genotypes.Semantic proximity Read ↗

A small interfering RNA (siRNA) database for SARS-CoV-2Semantic proximity Read ↗

Generation of small interfering RNA (siRNA) database from SARS-CoV-2 genome sequencesSemantic proximity Read ↗

Computational Identification of Small Interfering RNA Targets in SARS-CoV-2Semantic proximity Read ↗

Potential siRNA Molecules for Nucleoprotein and M2/L Overlapping Region of Respiratory Syncytial Virus: In Silico DesignSemantic proximity Read ↗

Design of Potential RNAi (miRNA and siRNA) Molecules for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Gene Silencing by Computational MethodSemantic proximity Read ↗

An RNAi in silico approach to find an optimal shRNA cocktail against HIV-1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.