Article
Mutational analysis of Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP).
Archives of biochemistry and biophysics - 15 Aug 2006
Tada Yukiyo, Nimura Takaki, Sueyoshi Noriyuki, Ishida Atsuhiko, Shigeri Yasushi, Kameshita Isamu
Abstract excerpt
Ca(2+)/calmodulin-dependent protein kinase phosphatase (CaMKP) is a member of the serine/threonine protein phosphatases and shares 29% sequence identity with protein phosphatase 2Calpha (PP2Calpha) in its catalytic domain. To investigate the functional domains of CaMKP, mutational analysis was carried out using various recombinant CaMKPs expressed in Escherichia coli. Analysis of N-terminal deletion mutants...
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