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Article

Low frequency of large genomic rearrangements of BRCA1 and BRCA2 in western Denmark.

Cancer genetics and cytogenetics - 15 Jul 2006

Thomassen Mads, Gerdes Anne-Marie, Cruger Dorthe, Jensen Peter K A, Kruse Torben A

Abstract excerpt

Germline mutations in BRCA1 and BRCA2 predispose female carriers to breast and ovarian cancer. The majority of mutations identified are small deletions or insertions or are nonsense mutations. Large genomic rearrangements in BRCA1 are found with varying frequencies in different populations, but BRCA2 rearrangements have not been investigated thoroughly. The objective in this study was to determine the frequency...

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Source

Identifiers

PMID: 16843109
DOI: 10.1016/j.cancergencyto.2005.12.016

Genes

BRCA1
BRCA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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