Article
[Current situation of researches on the molecule mechanism of hormone refractory prostate cancer].
Zhonghua nan ke xue = National journal of andrology - 1 Jun 2006
Yang Nian-qin, Wang Yi-xin
Abstract excerpt
Most cases of prostate cancer become hormone refractory after 12 to 18 months of androgen deprivation therapy. The etiology of the disease is thought to be multifactorial, associated with genetic, dietary, and environmental factors. The article reviews the current situation of researches at home and abroad on the molecule mechanism of hormone refractory. It expounds the influence of the androgen receptor and its...
Topics
- Androgens
- Animals
- Apoptosis
- Genes, p53
- Humans
- Male
- Mutation
- Oncogene Protein p21(ras)
- Prostatic Neoplasms
- Rats
- Receptor, EphB2
- Receptors, Androgen
