Article
New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108).
Structure (London, England : 1993) - 15 Mar 1998
Müller A, Müller J J, Muller Y A, Uhlmann H, Bernhardt R, Heinemann U
Abstract excerpt
BACKGROUND: Adrenodoxin (Adx) is a [2Fe-2S] ferredoxin involved in steroid hormone biosynthesis in the adrenal gland mitochondrial matrix of mammals. Adx is a small soluble protein that transfers electrons from adrenodoxin reductase (AR) to different cytochrome P450 isoforms where they are consum...
Topics
- Adrenodoxin
- Animals
- Binding Sites
- Cattle
- Crystallography, X-Ray
- Cytochrome P-450 Enzyme System
- Electron Transport
- Ferredoxin-NADP Reductase
- Ferredoxins
- Iron
- Mutation
- Protein Conformation
- Protein Folding
- Protein Structure, Secondary
- Recombinant Proteins
- Solvents
- Sulfur