Effector Roles of Putidaredoxin on Cytochrome P450cam Conformational States.

doi:10.1021/jacs.6b04110

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Effector Roles of Putidaredoxin on Cytochrome P450cam Conformational States.

Journal of the American Chemical Society - 17 Aug 2016

Liou Shu-Hao, Mahomed Mavish, Lee Young-Tae, Goodin David B

Abstract excerpt

In this study, the effector role of Pdx (putidaredoxin) on cytochrome P450cam conformation is refined by attaching two different spin labels, MTSL or BSL (bifunctional spin-label) onto the F or G helices and using DEER (double electron-electron resonance) to measure the distance between labels. Recent EPR and crystallographic studies have observed that oxidized Pdx induces substrate-bound P450cam to change from...

Topics

Binding Sites
Camphor
Camphor 5-Monooxygenase
Carbon Monoxide
Crystallography, X-Ray
Electron Spin Resonance Spectroscopy
Ferredoxins
Ligands
Mutation
Oxidation-Reduction
Oxygen
Protein Binding
Protein Conformation
Pseudomonas putida
Spin Labels

Source

Open in PubMed

Identifiers

PMID: 27452076
DOI: 10.1021/jacs.6b04110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics