Article
Effector Roles of Putidaredoxin on Cytochrome P450cam Conformational States.
Journal of the American Chemical Society - 17 Aug 2016
Liou Shu-Hao, Mahomed Mavish, Lee Young-Tae, Goodin David B
Abstract excerpt
In this study, the effector role of Pdx (putidaredoxin) on cytochrome P450cam conformation is refined by attaching two different spin labels, MTSL or BSL (bifunctional spin-label) onto the F or G helices and using DEER (double electron-electron resonance) to measure the distance between labels. Recent EPR and crystallographic studies have observed that oxidized Pdx induces substrate-bound P450cam to change from...
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