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Use ofLactococcus lactisExpressing Pili from Group BStreptococcusas a Broad‐Coverage Vaccine against Streptococcal Disease

5 Jul 2006

Abstract excerpt

Recent data indicate that the human pathogen group B Streptococcus (GBS) produces pilus-like structures encoded in genomic islands with similar organization to pathogenicity islands. On the basis of the amino acid sequence of their protein components, 3 different types of pili have been identified in GBS, at least 1 of which is present in all isolates. We recently demonstrated that recombinant pilus proteins...

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PMID: 16826481
DOI: 10.1086/505433

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